Online exhibition design: 3d user interface VS 2d (flat) interface

I am planning to design an online exhibition platform. I looked at existing exhibition platforms for reference and found that most of them have 3d interfaces.

Here is an example of fancier 2d interface on Youtube.

Some are full 3d with navigating like in-game. I think it would be a bad UX with such an interface.

I don't think it's a good idea to have a 3d interface as I was uncomfortable in navigation and think that a good flat design will work better.

So my question is: can a flat interface be better than 3d interface? What factors should I consider to find the trade-off between these two?