Is there any limit as to "how repeatedly an interaction model/behaviour can be used"?

is there any study or anything which points out whether its ok or not "to use a particular interaction model/gesture" over and again/ repeatedly for a single long task..for eg..using drop down interaction for selection process of lets say 20 items..is it ok or do you think it will too repetitive an interaction even though this interaction of drop down selection is most suitable for the current task?