Design/development frameworks equally suitable for both desktop and mobile views

I am quite a new to (or way too old for) a modern HTML, and i had to develop simple UI. I need to support 2 types of screen in it:

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So UI consists of a menu, and content, for instance, a text with a picture aside. In my times layouts were done via <table><tr><td>.. or <frameset>..-like stuff. But one scheme is <td>item1</td><td>item2</td> and the other is <tr>item1</tr><tr>item2</tr>. In a static .htm text file i can write only one variant.

What are some of the common development frameworks that can support both views equally? Most of the common development frameworks like Bootstrap take a 'mobile first' approach to responsive design, which means that desktop views are often less than optimal, while development frameworks like Material Design can be difficult to interpret.

Are there development frameworks known for its suitability for both desktop and mobile views?