Clicker Training – Effects when using computer mouse and keyboard?

I am kinda wondering whether the clicking sound of a computer mouse has a passive or active effect like the one used in clicker trainer.

In clicker training, a trainer would use a sound cue (can also be vocal) to teach an animal that it showed the wanted behavior. This training method is used when a trainer isn't able to communicate to the animal in another way, hat exact part of an execution he wants to reward.

However, when we use the computer, we are exposed to comparable cues all the time.

Does it have similar rewarding effects on humans on "normal" usage?

Is there hard- or software, that already rewards this kind of behavior? Like clicker as the paperclip game where you in summary do not much more than clicking a button over and over again?

I would also be interested on qualitative good scientific studies on this topic.