Can screen readers interpret Unicode styles fonts such as bold and italics?

I have seen serval social media channels using Unicode to make part of their text bold or italicised on websites such as Twitter, where this sort of thing is usually not possible.

It crossed my mind that this could interfere with accessibility for screen reader users - especially since on Twitter, styled text seems to count for double the characters (e.g. "?????" counts as 10 characters).

Can screen readers read this sort of text as easily as regular text?

Examples:

????? ???? ??????

????? ???? ??????