Are URLs important for the user?

I am developing a web application, and I am wondering if it is important to have URLs which are explicit and informative for the user or not? Or should I just focus on the good design of the webpages themselves as the whole attention of the user goes there?

EDIT:

I am not asking about the base URL (like: https://www.example.com) but about the URLs related to the different parameters of the site.

For example:

For one particualr page, should I have:

https://www.example.com/1/2/3/4/

Or:

https://www.example.com/continent/1/country/2/region/3/town/4/